Summary

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I'm a computational biologist, developing new methods to infer 3D structures of protein complexes, from NMR data.

Research experience

From Dec 2012: CNRS Researcher

UMR 3528, Unité de Bioinformatique Structurale, Institut Pasteur, Paris

May 2009 - Nov 2012 : Postdoctoral position

Leibniz-Institut für Molekulare Pharmakologie, NMR-supported Structural Biology, Berlin, Germany
Structure calculation of protein complexes and developement of dedicated methods for solid-state NMR.

Sep 2006 - Sep 2009: PhD student

Institut Pasteur - Unité de Bioinformatique Structurale - Paris, France and Freie Universität Berlin, Berlin, Germany
"NMR structure calculation of symmetric oligomers" co-supervised by Prof M. Nilges (Institut Pasteur, Paris) and Prof H. Oschkinat (FMP, Berlin)

April 2005 - Sep 2006: Bioinformatics Engineer

Institut Pasteur - Laboratoire de Biochimie Théorique (IBPC, CNRS) / Unité de Bioinformatique Structurale (Institut Pasteur), Paris
Developments of protocols for NMR structure determination in torsion angle space (coll. with A. Mazur, IBPC and Thérèse Malliavin, Institut Pasteur)
Automated NOE assignment and structure determination of symmetric homo-dimers with ARIA (coll. with M. Nliges, Institut Pasteur)

Oct 2004 - Mar 2005: Bioinformatics Engineer

Institut Pasteur - Unité de Bioinformatique Structurale - Paris, France
Comparison of different torsion angle approaches for NMR structure determination. (coll. A. Mazur, T. Malliavin, and M. Nilges)

April 2004 - July 2004 : Bioinformatics Engineer

Institut National Supérieur de la Recherche Médical - Equipe de Bioinformatique Génomique et Moléculaire - Paris, France.
"Analysis and prediction of transmembrane alpha-helices orientation" (coll. C. Etchebest, EBGM, Paris).

Languages

French: mother tongue
English: fluent
German: basic (but getting much better since I moved to Germany !)

Education

2009 : Dr. rer. nat. (PhD) Joint supervision Prof. M. Nilges (Institut Pasteur, Paris) and Prof. Oschkinat (Freie Universitat Berlin)
"Structure calculation of proteins from solution and solid-state NMR data: Application to monomers and symmetric aggregates." [Full text]

2003 : Master 2 : Master Bioinformatics and Applied Genomics (Grade Bien, Major)
Ecole Supérieure de Biotechnologie de Strasbourg (European School of the Higher Rhine Universities), Louis Pasteur University, Strasbourg, France.
Master thesis at Institut National de la Recherche Agronomique (INRA) at the URPVI (Protéines végétales et Interactions) in Nantes, France. Supervisor: Dominique Tessier "Analyse in silico des données de ponts disulfures. Recherche de Règles d'Association. "

2002: Master 1: Maîtrise Molecular and Cellular Biochemistry (Grade Assez Bien)
Louis Pasteur University, Strasbourg, France.